Amr Nassrallah

Associate Professor
amr.nassrallah@ejust.edu.eg

Personal Info

01096278078

BIO

My research focuses on the interdisciplinary application of molecular biology, biochemistry, and nanotechnology in both plant and human systems. I am particularly interested in developing nano-based drug and biomolecule delivery systems, investigating cellular and molecular responses in cancer and plant models, and advancing transgenic technologies. I also explore natural product extraction, microbial fermentation, and sustainable bioprocessing of agro-waste. By integrating cell imaging, proteomics, and genetic tools, I aim to translate fundamental research into practical applications in biomedicine, agriculture, and environmental science.


Awards

  • 2020 Cairo University Encouragement Award, Cairo, Egypt
    Recognized for outstanding research contributions in the fields of molecular biology and biotechnology.

  • 2017 Postdoctoral Fellowship, National Center for Biotechnology (CNB-CSIC), Madrid, Spain
    Awarded for research on chromatin remodeling and protein degradation in plant light response pathways.

  • 2011–2016 "la Caixa" Foundation International PhD Fellowship, Madrid, Spain
    Competitive four-year PhD fellowship awarded by "la Caixa" Foundation to conduct doctoral research in Plant Molecular Genetics at CNB-CSIC and Universidad Autónoma de Madrid.


Impacted Journal

1.      Said, K., Nassrallah, A., El-Shibiny, A., & Mohamed, G. G. (2025). Methylene Blue-Encapsulated Superparamagnetic Iron Oxide Nanoparticles Coupled With NIR-Responsive Upconversion Carbon Dots As Novel Nanoplatform For Improved Photodynamic Therapy. Surfaces and Interfaces, 106572.

2.      Hamed, A. M., Abd El-Maksoud, A. A., Hassan, M. A., Tsakali, E., Van Impe, J. F., Ahmed, H. A., & Nassrallah, A. A. (2024). Enhancing functional buffalo yogurt: Improving physicochemical properties, biological activities, and shelf life using marjoram and geranium essential oils. Journal of Dairy Science107(9), 6437-6450

3.      Abouelenein, M. G., El-Rashedy, A. A., Awad, H. M., El Farargy, A. F., Nassar, I. F., and Nassrallah, A. (2023). Synthesis, molecular modeling Insights, and anticancer assessment of novel polyfunctionalized Pyridine congeners. Bioorganic Chemistry141, 106910.

 

4.      Ahmed, H. A., Nassrallah, A. A., Abdel-Raheem, M. A., & Elbehery, H. H. (2023). Lemon peel essential oil and its nano-formulation to control Agrotis ipsilon (Lepidoptera: Noctuidae). Scientific Reports13(1), 17922.

 

 

5.      Elarabi, N. I., Abdelhadi, A. A., Nassrallah, A. A., Mohamed, M. S., & Abdelhaleem, H. A. (2023). Biodegradation of isoproturon by Escherichia coli expressing a Pseudomonas putida catechol 1, 2-dioxygenase gene. AMB Express13(1), 101.

6.      El-Sawy ER, El-Shahid ZA, Soliman AAF, Nassrallah A, Abdelwahab AB, Kirsch G, Abdelmegeed H. Synthetic Analogs of Marine Alkaloid Aplysinopsin Suppress Anti-Apoptotic Protein BCL2 in Prostate Cancer. Molecules. 2022 Dec 23;28(1):109. doi: 10.3390/molecules28010109. PMID: 36615305; PMCID: PMC9821956.

 

7.      Soliman, I.A., Hasanien, Y.A., Zaki, A.G. et al. Irradiation impact on biological activities of Anthraquinone pigment produced from Talaromyces purpureogenus and its evaluation, characterization and application in beef burger as natural preservative. BMC Microbiol 22, 325 (2022). https://doi.org/10.1186/s12866-022-02734-4

 

8.      AbouAitah, K.; Soliman, A.A.F.; Swiderska-Sroda, A.; Nassrallah, A.; Smalc-Koziorowska, J.; Gierlotka, S.; Lojkowski, W. Co-Delivery System of Curcumin and Colchicine Using Functionalized Mesoporous Silica Nanoparticles Promotes Anticancer and Apoptosis Effects. Pharmaceutics 202214, 2770. https://doi.org/10.3390/pharmaceutics14122770

 

9.      Hasanien, Y. A., Nassrallah, A. A., Zaki, A. G., & Abdelaziz, G. (2022). Optimization, purification, and structure elucidation of anthraquinone pigment derivative from Talaromyces purpureogenus as a novel promising antioxidant, anticancer, and kidney radio-imaging agent. Journal of Biotechnology356, 30-41.

 

10.   Ashwak Abdel-moeim Hassan, Yasser Essam Elenany, Amr Nassrallah, Weiwei Cheng, Ahmed A. Abd El-Maksoud (2022). Royal jelly improves the physicochemical properties and biological activities of fermented milk with enhanced probiotic viability, LWT,155,112912.

 

11.   El-Maksoud, A., Makhlouf, A., Altemimi, A. B., El-Ghany, I., Nassrallah, A., Cacciola, F., & Abedelmaksoud, T. G. (2021). Nano Milk Protein-Mucilage Complexes: Characterization and Anticancer Effect. Molecules, 26(21), 637.

 

12.   Ahmad Mohammad Salamatullah, P. Subash-Babu, Amr Nassrallah, Ali A. Alshatwi, Mohammed Saeed Alkaltham,Cyclotrisiloxan and β-Sitosterol rich Cassia alata (L.) flower inhibit HT-115 human colon cancer cell growth via mitochondrial dependent apoptotic stimulation,Saudi Journal of Biological Sciences,2021

13.   Habiba Abdelaziz Ahmed; Ahmed Mahmoud Aboul-Enein; Faten abou-Elella; Salah Hamza Elmahdy Salem; Hanan Farouk Aly; Amr Nassrallah; Zeinab Salama2021 Nano-Formulations of Hesperidin and Essential Oil Extracted from Sweet Orange Peel: Chemical Properties and Biological Activities. EJCHEM, 64(9), 5373-5385

 

14.   Ahmed, H. A., Salama, Z. A., Salem, S. H., Aly, H. F., Nassrallah, A., Abou-Elella, F., & Aboul-Enein, A. M. (2021). Lyopene Nanoparticles Ameliorate The Antioxidants, Antimicrobial And Anticancer Potencies Of Tomato Pomace. Egyptian Journal of Chemistry, 64(7), 3739-3749.

 

15.   Kamal KY, Khodaeiaminjan M, Yahya G, El-Tantawy AA, Abdel El-Moneim D, El- Esawi MA, Abd-Elaziz MAA, Nassrallah AA. Modulation of cell cycle progression and chromatin dynamic as tolerance mechanisms to salinity and drought stress in maize. Physiol Plant. 2021 Jun;172(2):684-695.

 

16.   Aboul-Soud, M.A.M.; Ashour, A.E.; Challis, J.K.; Ahmed, A.F.; Kumar, A.; Nassrallah, A.; Alahmari, T.A.; Saquib, Q.; Siddiqui, M.A.; Al-Sheikh, Y.; El-Shemy, H.A.; Aboul-Enein, A.M.; Alghamdi, K.M.; Jones, P.D.; Giesy, J.P. Biochemical and Molecular Investigation of In Vitro Antioxidant and Anticancer Activity Spectrum of Crude Extracts of Willow Leaves Salix safsaf. Plants 2020, 9, 1295.

17.   Salwa M. El-Hallouty, Ahmed A. F. Soliman, Amr Nassrallah, Ahmad Salamatullah, Mohammed Saeed Alkaltham, Khaled Y. Kamal, Eman A. Hanafy, Hanan S. Gaballa and Mourad A. M. Aboul-Soud. (2020).Crude Methanol Extract of Rosin Gum Exhibits Specific Cytotoxicity Against Human Breast Cancer Cells via Apoptosis Induction. Anticancer Agents Med Chem. 20(8):1028-1036

 

18.   Khaled Y. Kamal, Mortaza Khodaeiaminjan, Ahmed A. El-Tantawy, Diaa A. Moneim,Asmaa Abdel Salam, Salwa M. A. I. Ash-shormillesy, Ahmed Attia, Mohamed A. S. Ali,Raúl Herranz, Mohamed A. El-Esawi, Amr A. Nassrallah and Mohamed Fawzy Ramadan(2020). Evaluation of growth and nutritional value of Brassica microgreens grown under red, blue and green LEDs combinations. Physiol. Plant. 169: 625–638.

 

19.   Heba M. Abo-Salem, Amr Nassrallah, Ahmed A.F. Soliman, Manal S. Ebied, Mohamed E. Elawady, Sayeda A. Abdelhamid, Eslam R. El-Sawy, Yazeed A. Al- Sheikh and Mourad A. M. Aboul-Soud (2020). Synthesis and Bioactivity Assessment of Novel Spiro Pyrazole-Oxindole Congeners Exhibiting Potent and Selective in vitro Anticancer Efects. Molecules. 25(5):1124, 1-19

 

20.   Amr Nassrallah, Martin Rougee, Clara Bourbousse, Stephanie Drevensek, Sandra Fonseca, Elisa Iniesto, Ouardia Ait-Mohamed, Anne-Flore Deton-Cabanillas, Gerald Zabulon, Ikhlak Ahmed, David Stroebel,Vanessa Masson, Berangere Lombard, Dominique Eeckhout, Kris Gevaert, Damarys Loew, Auguste Genovesio, Cecile Breyton, Geert de Jaeger, Chris Bowler, Vicente Rubio, Fredy Barneche. (2018). DET1-mediated degradation of a SAGA- like deubiquitination module controls H2Bub homeostasis. eLife;7: e37892. DOI:10.7554/eLife.37892


International Conference

1. Amr Nassrallah, Sandra Fonseca, Vicente Rubio. New links between chromatin remodelling and photomorphogenesis in Arabidopsis. XII Meeting of plant molecular biology. Oviedo-Spain. 22-24 Junio 2016
2. Amr Nassrallah, Sandra Fonseca, Vicente Rubio. Identification of deubiquitinase subcomplex of SAGA in Arbidopsis. XII Meeting of plant molecular biology. Cartagena-Spain. 11-23 Junio 2014
3. Elisa Iniesto, Maria Luisa Irigoyen, Amr A. Nassarallah, Diaa Abd-ElMoneim, Jennifer Esteban, Xin Wang Deng y Vicente Rubio. Integración de
señales de estrés abiótico y del desarrollo mediada por DDA1 y complejos ubiquitina ligasa CRL4. XI Meeting of plant molecular biology. Segovia Junio 2012.
4. Maria Luisa Irigoyen, Elisa Iniesto, Amr A. Nassarallah, Diaa Abd-El Moneim, Jennifer Esteban, Xin Wang Deng y Vicente Rubio. Integration of
abiotic stress and developmental signals mediated by DDA1 and CRL4
ubiquitin ligases. International Conference and Annual Meetings of the DFGSPP1365. Munich (Germany). Septiembre 2012.

5-Participation in the Regional Linkages workshop co-organized y JKUAT and AFRICA-ai-JAPAN Project Phases 2 (JICA). JKUAT, 2-10 March 2024. Nairobi, Kenya.
6- Participation in the European workshop on plant chromatin Centre for Plant Biotechnology and Genomics CBGP, 29-30 August 2013. Madrid, Spain.


Funded Research Grants

 

·       Project title: PI " Development of a label-free new technology based on Raman spectroscopy and artificial intelligence for food safety" (reference number: 48634). Financing entity: Science and Technology Development Fund STDF. 2024 2026.

·       Project title: "Promiscuity of receptors in interaction hormonals and evaluation of its potential biotechnology for sustainable agriculture " (reference number: BIO2010-18820). Financing entity: Ministerio de Ciencia e Innovación (Plan Nacional de Biotecnología) 2014 2016.

·        Project title: "Regulation of ubiquitination machinery in the control of development and stress response in plants" (Contract number: BIO2013-44407- R). Financing entity: Ministerio de Ciencia e Innovación (Plan Nacional de Biotecnología) 2011 2013

·       Project title: Production of Natural Biological Active Formulas as Antioxidant, Anti-mutagenic and Anti-carcinogenic Drugs Financing entity: Egyptian Ministry of scientific research 2010 until I moved to Spain.

·       Project title: Single natural compounds and synergistic effects as antileukemic agents at molecular level Financing entity: National CFIDS Foundations Inc, Needham, MA 02492- 3931, USA. 2008-20011.